WebMar 2, 2024 · The risks of leukemia after platinum-based chemotherapy were 2.4, 3.8, and 5.6, respectively, less than 2 years, 2 to 4 years, and 5 or more years after the diagnosis of ovarian cancer (range, 1.3 ... WebFeb 7, 2024 · Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such as lack of selectivity, high systemic toxicity, and drug resistance, seriously limit their clinical application. With advancements in nanotechnology and chemical synthesis, Pt ...
Platinum-Based Chemotherapy plus Cetuximab in Head and Neck …
WebJan 23, 2024 · Effective and well tolerated treatment for platinum-resistant ovarian cancer remains a substantial unmet need. Despite the introduction of targeted and immunological therapies for its management, platinum-based chemotherapy with carboplatin or cisplatin remains the backbone of treatment. WebJul 17, 2012 · Platinum-based chemotherapy drugs are among the most powerful and widely used against cancer. However, they have toxic side effects, and tumors can become resistant to them. Cisplatin, the... nintendo switch orange and purple joycons
Electrolyte disorders with platinum-based …
WebCisplatin, a class of platinum-containing anticancer drugs for the treatment of solid tumors, is a substrate of OCT2 and MATE1/MATE2-K. OCT2 is expressed in the basolateral membrane of proximal tubules and mediates the transport of cisplatin from the blood to proximal tubule cells. WebFeb 1, 2024 · Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body. This medicine is to be given only by or under the direct supervision of a doctor. WebCisplatin was administered as the initial platinum-based treatment in 149 patients (67%) in the cetuximab group and in 135 patients (61%) in the chemotherapy-alone group. nintendo switch orangeburg